Podcasts from The Cochrane Library

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Cochrane produces systematic reviews which are recognized as the highest standard in evidence-based health care resources. Listen to Cochrane review authors explain in plain language the evidence and findings of their high-impact reviews. In 5 minutes or less, healthcare professionals to patients and families can understand the latest trusted evidence to help make better informed decisions.
Updated: 20 min 56 sec ago

Which medicines, taken by mouth or injected, work best to treat a skin condition called plaque psoriasis?

Tue, 11/22/2022 - 16:12

The Cochrane Skin Group has produced some of the largest Cochrane reviews, providing a “one stop shop” for people interested in a wide range of interventions for a particular skin condition. One such example is the review of systemic medicines to treat psoriasis, which was updated for the fourth time in May 2022. We asked two of the authors, Laurence Le Cleach, head of the French satellite of the Cochrane Skin group and dermatologist at Henri Mondor hospital, AP-HP in France and Emilie Sbidian, a dermatologist working at the same hospital, to describe the findings.

Hydroxyurea (also known as hydroxycarbamide) for people with sickle cell disease

Mon, 11/14/2022 - 20:19

Several Cochrane Reviews evaluate treatments for sickle cell disease, which can cause a huge burden for patients and their families. The review on the effects of hydroxyurea was updated in September 2022 by Angela Rankine-Mullings from the Sickle Cell Unit, Caribbean Institute for Health Research at The University of the West Indies in Jamaica and Sarah Nevitt, from the Department of Health Data Science, University of Liverpool in UK. We asked Angela to outline the need for the review and its latest findings in this podcast.

Do school-based physical activity interventions increase moderate to vigorous physical activity and improve physical fitness among children and adolescents?

Wed, 11/09/2022 - 16:00

Identifying ways to help people be physically active should help improve their health and well-being, and prevent premature deaths. There are several relevant Cochrane reviews and one published in September 2021 looks at school-based programs. Here's the review's first author, Sarah Neil-Sztramko, from McMaster University in Canada to tell us about the importance of the review and its findings.

What is the accuracy of different combinations of ultrasound imaging and blood tests to diagnose ovarian cancer in women before and after the menopause?

Wed, 11/09/2022 - 15:28

Hundreds of Cochrane reviews have been published over the last 25 years relevant to the diagnosis and treatment of a wide range of cancers, including ovarian cancer. In a new review from July 2022, Clare Davenport, from the University of Birmingham in the UK, and colleagues examined the evidence on the use of multiple tests to detect it and she tells us what they found in this podcast.

Periodic change of body position under phototherapy in term and preterm neonates with hyperbilirubinaemia

Thu, 10/13/2022 - 15:42

Some new-born babies suffer from jaundice and there are several Cochrane reviews of possible ways to treat it, including the use of phototherapy. These reviews were added to in March 2022 with a new review of the effects of changing the baby’s position under the phototherapy. Lead author, Anu Thukral from the All India Institute of Medical Sciences tells us about the findings in this podcast.

Mental health support in the community for refugee children and adolescents in high-income countries

Tue, 10/04/2022 - 14:07

The Cochrane Common Mental Disorders Group has published more than 200 reviews and, in May 2022, they added a new review of community‐based interventions for improving the mental health of refugee children and adolescents in high‐income countries. One of the authors, Noortje Uphoff who works with the Group at the University of York in the UK, tells us more in this podcast.

Which combinations of medicines are best for the prevention and treatment of anaemia in people with cancer?

Fri, 09/23/2022 - 13:56

Cochrane has produced several systematic reviews of interventions that might help people suffering from anaemia. In this podcast, Claire Iannizzi talks with lead author Anne Adams, both from the University Hospital Cologne in Germany, about a review of intravenous, oral or no iron in combination with erythropoiesis-stimulating agents for cancer patients with anaemia, which was published for the first time in June 2022.

How accurate are rapid antigen tests for diagnosing COVID-19?

Tue, 09/20/2022 - 20:37

Several of the Cochrane reviews in our collection for COVID-19 relate to diagnosis and the second update for one of these, on the use of rapid point-of-care antigen tests was published in July 2022. Here's lead author Jacqueline Dinnes from the University of Birmingham in the UK to tell us what they found.

Control interventions in randomised trials for people with a mental health disorder

Tue, 09/20/2022 - 20:05

The Cochrane Methodology Review Group produces reviews that examine the methods used in research and, in April 2022, we published a new review of the effects of having different types of control group in trials among people with mental health disorders. Here's lead author, Erlend Faltinsen from Cochrane Denmark, to tell us about the review and its findings

Prophylactic cyclo-oxygenase inhibitor drugs to prevent morbidity and mortality in preterm infants

Fri, 09/02/2022 - 19:33

The Cochrane Neonatal Group is one of the largest Cochrane groups, with more than 400 reviews published, many of which relate to the care of babies born before they reach full-term. These reviews were added to in April 2022 with a new review of the use of cyclo-oxygenase inhibitors and, in this podcast, one of the group’s researchers, Abbey MacLellan, talks with lead author Souvik Mitra, a neonatologist and clinical epidemiologist at Dalhousie University and IWK Health in Halifax Canada about this network meta-analysis.

Rho kinase inhibitors for primary open-angle glaucoma and ocular hypertension

Fri, 09/02/2022 - 16:03

Glaucoma is a common eye condition and a major cause of blindness. There are several Cochrane reviews of ways to treat it and these were added to in June 2022 with a new review of a class of drugs called rho kinase inhibitors. We asked lead author, Josefine Freiberg from the University of Copenhagen in Denmark to tell us about the evidence in this podcast.

Antioxidants for male subfertility

Fri, 08/26/2022 - 20:11

The Cochrane Gynaecology and Fertility Group maintains a pair of reviews on the use of antioxidants in the treatment of subfertility. The review for males was updated in May 2022 and we asked Wiep de Ligny from the Radboud University Medical Center at Nijmegen in the Netherlands to tell us about the importance of the review and its latest findings in this podcast.

Cannabis and cannabinoids for people with multiple sclerosis

Thu, 08/25/2022 - 20:36

In May 2022, the Cochrane Multiple Sclerosis and Rare Diseases of the CNS Group published a new review of the effects of cannabis and cannabinoids for the treatment of people with multiple sclerosis. In this podcast, Silvia Minozzi, Co-ordinating Editor of the Cochrane Drugs and Alcohol Group and an author on the review talks with lead author and Co-ordinating Editor of the Cochrane Multiple Sclerosis Group, Graziella Filippini, about the review.

Do video-assisted instruments for inserting breathing tubes in adults work better than direct-view instruments and do they cause unwanted effects?

Thu, 08/11/2022 - 18:21

Anaesthetists use a variety of techniques to insert a breathing tube into a patient before an operation. These include using a rigid indirect videolaryngoscope and the Cochrane review comparing this with the traditional direct laryngoscope was updated in April 2022. In this podcast, two of the authors, Jan Hansel and Andy Rogers, who are from Manchester University NHS Foundation Trust and Royal United Hospitals Bath NHS Trust in the UK, chatted about the procedures.