Podcasts from The Cochrane Library
In March 2021, the Cochrane Neuro-Oncology Group published a series of eight new complex systematic reviews on priority topics for the brain tumour community. These were selected from the most important unanswered questions identified by people in this area using James Lind Alliance Priority Setting Partnership methods, which bring together patients and the public with practitioners. One of the reviews was a network meta-analysis of treatments for glioblastoma in the elderly and we asked lead author, Catherine Hanna from the University of Glasgow in the UK, to tell us about the condition and the review.
Many healthcare organizations use electronic health records to manage patient data and it has been suggested that it may be beneficial if patients can access their own records as well. In this podcast, Christina Cannellopoulos talks with lead author Elske Ammenwerth, a researcher in Medical Informatics from the University UMIT TIROL in Austria, about their Cochrane Review on this topic.
Is plasma from people who have recovered from COVID-19 an effective treatment for people with COVID-19?
Cochrane is producing a series of reviews to help decision makers respond to the COVID-19 pandemic. We’re keeping these reviews up to date as new evidence emerges and are now on the fourth version of our living review of convalescent plasma and hyperimmune immunoglobulin for COVID-19 patients, which was published in May 2021. In this podcast, Vanessa Piechotta speaks with one of the lead authors, Claire Iannizzi both from the University Hospital Cologne in Germany about the latest findings.
Postnatal depression affects many women in the months after having their baby and one of the early Cochrane Reviews looked at its treatment with antidepressants. The very first version of the review was published in 2001, and the review has been refreshed and updated again, with a new version published in February 2021. Here’s one of the authors, Claire Wilson from King’s College London in the UK, to tell us more.
Infectious diarrhoea is responsible for many thousands of deaths every day around the world and probiotics have been suggested as a possible treatment. The relevant Cochrane Review was updated for the second time in December 2020 and first author, Shelui Collinson from the Liverpool School of Tropical Medicine in the UK describes the latest findings in this podcast.
Which method of determining MGMT promoter methylation best predicts survival in people with glioblastoma treated with temozolomide?
In March 2021, the Cochrane Neuro-Oncology Group published a series of eight new systematic reviews on priority topics for the brain tumour community. These were selected from the most important unanswered questions identified by patients, the public and practitioners. In this podcast, Kathreena Kurian from the University of Bristol in the UK tells us about one of the reviews, which looked at the evidence on tests that might help to predict survival in patients who have received chemotherapy for glioblastoma.
The Cochrane Pregnancy and Childbirth Group has done many reviews of interventions that might prevent stillbirth and, in December 2020, they brought these together in an overview. In this podcast, one of the Group’s researchers, Dell Horey, talks with lead author Erika Ota, a professor at the St. Luke’s International University in Japan, about the findings.
As well as examining the evidence for starting patients on drug treatments, Cochrane Reviews also look at the relative benefits of stopping or continuing once someone has started taking them. This is the case with a February 2021 review of the effects of withdrawing or continuing two common classes of drug treatment for people with dementia. We asked lead author, Carole Parsons from Queen’s University Belfast in Northern Ireland to tell us what they found.
The Cochrane Anaesthesia Group has produced a wide variety of reviews relevant to procedures related to surgery. One of these looks at the use of melatonin for preoperative and postoperative anxiety in adults and it was updated in December 2020. We asked the new lead author, Bennedikte Madsen, from the Center for Perioperative Optimizationin Herlev Hospital in Denmark to tell us about the latest findings.
There are many Cochrane reviews about the management of patients in intensive care units, covering a wide range of interventions, and the second update of one of these, in December 2020, brought together the latest evidence on the effects of oral hygiene care. Here’s the lead author, Fang Hua from Wuhan University in China to tell us about the latest findings.
Cochrane has already produced many rapid reviews to help decision makers with their response to the COVID-19 pandemic and we are updating these to try to keep up with the accumulating evidence. In this podcast, lead author, Jake Burns from the University of Munich in Germany describes the latest findings of our review of the effects of control measures for international travel, which was updated in March 2021.
How does using technology to deliver pulmonary rehabilitation (PR) compare to centre-based PR, or no PR in people with chronic lung disease?
Many millions of people suffer from respiratory diseases such as chronic obstructive pulmonary disease, interstitial lung disease and bronchiectasis; and there are Cochrane Reviews for a wide range of interventions that might help, including drugs, devices and physical therapies. These were added to in January 2021 with a new review of the effects of providing pulmonary rehabilitation remotely and we asked the lead author, Narelle Cox from Monash University in Melbourne Australia, to tell us more in this podcast.
Alongside the hundreds of Cochrane Reviews of treatments for patients with cancer, there are many of ways to reduce the adverse effects of those treatments. In December 2020, we published the third update of one of these, looking at the effects of drugs to prevent venous thromboembolism in patients receiving chemotherapy. Marcello Di Nisio from the University "G. D'Annunzio" of Chieti-Pescara in Italy tells us about the latest findings in this podcast.
Xpert Ultra compared to Xpert MTB/RIF for diagnosing pulmonary tuberculosis and rifampicin resistance in adults
The Cochrane Library contains more than 140 Cochrane Reviews of the accuracy of diagnostic tests, covering a very wide range of conditions. One of these reviews, on a test used to detect tuberculosis in the lungs, was updated for the third time in February 2021 and Karen Steingart from the Liverpool School of Tropical Medicine in the UK speaks with first author, Jerry Zifodya from Tulane University in New Orleans, USA about the latest findings in this podcast. This review is also included in the Cochrane Library Special Collection for World Tuberculosis Day on 'Diagnosing tuberculosis'.
Our programme of rapid reviews for COVID-19 covers both the diagnosis and treatment of the disease and the reviews are being updated as new evidence becomes available. Among these is a review on imaging tests for diagnosing the condition, and we asked the lead author of the March 2021 update, Nayaar Islam from The Ottawa Hospital Research Institute in Canada, to describe the latest findings in this podcast.
The Cochrane Neonatal Group has produced more than 400 Cochrane Reviews over the last two decades, updating these periodically as new evidence becomes available. In March 2021, they published the update of their review of opioids for newborn babies requiring mechanical ventilation and we asked two co-authors of the review, Olga Romantsik and Matteo Bruschettini from Skåne University Hospital in Lund, Sweden, to tell us about the latest findings.
Within our growing collection of reviews relevant to COVID-19, we have several relating to its diagnosis. One of these, on the use of rapid point-of-care tests was updated in March 2021. Here's lead author Jacqueline Dinnes from the University of Birmingham in the UK to tell us what they found for antigen tests.
What are the benefits and risks of using virtual reality in a healthcare setting to distract children from pain?
The Cochrane Pain, Palliative and Supportive Care Group has more than 250 active reviews of the effects of a wide range of interventions. These were added to in October 2020 by a new review of the effects of using virtual reality to distract children undergoing painful procedures. We asked lead author, Veronica Lambert from Dublin City University in Ireland to tell us that they found.
Endometriosis is a common problem for hundreds of millions worldwide and Cochrane has produced more than two dozen reviews of a variety of possible treatments. These are kept up to date as new evidence becomes available and, in October 2020, the review of laparoscopic surgery was updated. In this podcast, former fertility patient and patient advocate, Katy Lindemann from Uber Barrens Club, speaks with senior author, James Duffy from King’s Fertility in the UK, about the latest findings.
What type of heart and blood vessel problems complicate COVID-19 infections, how common are they and what other medical conditions do these patients have?
We're producing a series of reviews covering the accumulating evidence on COVID-19, which are not only looking at the diagnosis and treatment of the disease but are also examining its links to other conditions. One of these reviews, on the effects of COVID-19 on cardiovascular health, was published in March 2021. In this podcast, co-author Keng Siang Lee, from the University of Bristol speaks with the first author, Pierpaolo Pellicori (photo) from the University of Glasgow in the UK about the findings.